SPV · TMS · New York, NY

Short fuse. Checked out. Not the man you were.

You're not sad. You're irritable, flat, and tired in a way sleep doesn't fix, and the people you love are getting the worst of it. Men are 50% less likely than women to be diagnosed with depression. And if you expect it to look like sadness, you may even miss the signs in yourself.

Why these treatments work

Help for when it feels like you've hit a wall

If the pills didn't help, or the trade-offs weren't worth it, you don't have to keep white-knuckling it. SPV and TMS work differently.

Different pathway

TMS and SPV target the brain through pathways the daily pills never touched.

Science-backed, FDA-cleared

TMS has been FDA-cleared since 2008; SPV has been FDA-approved since 2019.

Escape SSRIs' side-effects

No loss of libido or emotional numbness.

Tackling treatment resistance

Without taking a systemic drug every day for years.

A defined course

Unlike a daily prescription, your treatment plan has an end date.

Private

Nobody is notified, and checking your eligibility changes nothing about your current plan.

A different way to treat depression

TMS and SPV are two FDA-backed treatments for depression that work differently than the daily pills you've already tried. TMS uses targeted magnetic pulses, similar to an MRI, aimed at the exact brain region depression shuts down; no drug enters your bloodstream, so the rest of your body isn't affected. SPV works on glutamate, a different brain chemical than the serotonin system your prior prescriptions targeted. No daily pill, no guesswork. Sessions happen at a certified clinic, with a clear taper over time.

A different way to treat depression
  • FDA-approved or FDA-cleared, not experimental
  • Delivered in-clinic, under a psychiatrist's supervision
  • Built for men who've tried antidepressants that didn't work or weren't worth the trade-offs
  • A defined course with an end date, not an open-ended prescription
Am I a candidate for SPV or TMS?

How they work

TMS uses magnetic pulses, similar to an MRI, aimed at the specific brain region depression quiets. No drug enters your bloodstream, so the rest of your body isn't dosed. SPV works on glutamate, a different brain chemical than the serotonin system the pills targeted. Many people notice a shift within days rather than weeks.

Key stats & research

60%+

Of patients whose depression hadn't responded to medication had a clinically meaningful response after a course of TMS.

https://pmc.ncbi.nlm.nih.gov/articles/PMC12721854/

33%

Of TMS patients reached remission, meaning symptoms dropped below the level a clinician would call depression.

https://pmc.ncbi.nlm.nih.gov/articles/PMC12721854/

21.4 points

Average drop in depression severity scores (MADRS) after four weeks of SPV plus a new oral antidepressant, with a measurable difference at 24 hours.

https://www.ajmc.com/view/transform2-results-on-esketamine-published-along-with-caveats

2008 / 2019

Are the years the FDA first cleared TMS for medication-resistant depression and approved SPV for treatment-resistant depression.

https://www.fda.gov/news-events/press-announcements/fda-permits-marketing-transcranial-magnetic-stimulation-treatment-obsessive-compulsive-disorder

What we offer

Two FDA-Backed routes to thriving.

SPV · FDA-approved

A nasal spray that can work fast.

SPV (esketamine) acts on the glutamate system. This is a different brain pathway than used by SSRIs. In the original studies, an effect on depression was measurable within 24 hours. Sessions happen in-clinic with two hours of monitoring care. • FDA-approved since 2019 • In-clinic, 2-hour visit • Twice weekly × 4 weeks, then possible maintenance sessions

TMS · FDA-cleared

Depression treatment using magnets.

TMS is a non-invasive physical therapy using gentle magnetic pulses to reawaken the brain region depression can dull. No drugs, no sedation, and no recovery time. Sessions are about 20 minutes and you drive yourself home. • FDA-cleared since 2008 • ~20 min, drive yourself home • 5 days a week × 6 weeks, then taper

You don't need to choose between SPV and TMS today. Your psychiatrist will help you weigh each approach and find the right option during your free evaluation, based on your history and your goals.

Your brain is healing

What to expect

The evaluation

About 45 to 60 minutes with a licensed psychiatrist, plus a brief intake call beforehand to verify insurance and gather records.

A clear next step

Most men leave the evaluation with a recommendation and a starting date if they want to proceed.

No pressure

There's no obligation to start treatment after the evaluation.

Insurance & cost

We'll handle the paperwork & process, together.

Both SPV and TMS are covered by most major commercial insurance plans and Medicare for adults whose depression hasn't responded to medication. Each one needs its own prior authorization. Once we've got the green light from the psychiatrist, Psycle Health and your partner clinic will handle the paperwork for whichever path you choose. We check your benefits, prepare the approval request, and tell you exactly what your out-of-pocket cost will look like before you start, at no charge.

Most plans

Commercial and Medicare cover both options with prior authorization

1 - 2 weeks

Typical insurance approval turnaround

Free

Evaluation and benefits check at no cost

In their words.

Nick P.

"We both struggled with the after-effects of COVID. I dealt with fatigue that lasted about four months and gained a lot of weight because of it. I started working out, but kept hitting a wall; I just didn't have the energy. Now I have energy, motivation, and a lot more confidence that the work I'm putting in is actually paying off. Looking back, I can give myself credit. I was genuinely sick, and I needed something to help me through it."

Nick P.

Scott T.

"I was in the darkest period of my life, and SPV helped me out of it. It gave me a completely different way of thinking about my problems, a new perspective. Instead of dwelling, I learned to approach things proactively and pragmatically. Now when something difficult comes up, I don't spiral, I process it and move on."

Scott T.

Dave S.

"When medication doesn't give you the results you're hoping for, TMS offers another path, one that helps you feel better without changing who you are. Antidepressants made me feel like a different version of myself. With TMS, I found relief and reconnected with a part of me that had been asleep for a long time."

Dave S.

Marcus B.

"It has changed my life in every way. I'm a much happier person, more outgoing, and I'm finally sleeping well. It's been like a miracle. If you're struggling, give this a try. I guarantee you won't regret it."

Marcus B.

Doug M.

"I sat in that chair for an hour and came out with thirty years of junk cleared out of my head. That, to me, was a miracle. I haven't felt this good in probably three decades. It works. You can go from feeling like trash to feeling normal in the span of two hours. If you're on the fence, don't be. They'll treat you well, and you'll feel amazing when you leave."

Doug M.

Brian N.

"I wasn't in a good place at all. Within 24 hours, I experienced a couple of deaths close to me and just couldn't function. I reached out for help, and was told to see a psychiatrist and get on medication. I didn't want to spend the rest of my life on a pill, so I looked for something different. From the moment I walked in, I knew I was in the right place. They made me feel comfortable, with no judgment at all, and that made all the difference. They actually care, they want to understand what's really going on, not just prescribe something. I feel like I'm finally getting somewhere, and I feel better than I have in a long time."

Brian N.

Kristen H.

"The first time I tried SPV Therapy, I noticed the change immediately. Before, I was living with anxiety and depression, on four different medications, trying to find relief without wanting all the side effects that came with them. I decided to give SPV Therapy a try, and it changed my life completely."

Kristen H.

Denise N.

"The medication itself is wonderful, but the support around it is what really makes the difference. I've been able to continue with psychotherapy sessions after my SPV treatments, which helped me integrate everything I was learning. It's been an incredible experience, and I wouldn't go anywhere else."

Denise N.

Carol J.

"During treatment, I found myself revisiting parts of my childhood, including people who had hurt me deeply. What surprised me was how much love and empathy I felt toward them in that moment. I actually felt sorry for them, wondering what happened to make them hurt me the way they did. It was the first time I ever felt real peace toward them."

Carol J.

Judy P.

"I noticed a real difference in my behavior, my mood, my motivation. I was in a very deep depression, and medication just wasn't working. Then I found out about SPV, and it helped me move past that depression so much faster than I expected. The people caring for me were wonderful and genuinely concerned about my wellbeing. I wouldn't go anywhere else."

Judy P.

Nancy T.

"A friend recommended SPV when I was in a really dark place. Within two weeks, I noticed a real shift, in my mood, my energy, the way I showed up every day. I was happier, more motivated, getting things done at work again. I knew something had to change, and this is what changed it. SPV gave me my life back."

Nancy T.

Julie S.

"Within two weeks, I noticed a real difference, smiling more, getting out of the house, showing up for my life again. The team makes it easy too. They respond fast and make you feel like you actually matter. I'm grateful every day. I'm simply a different person now."

Julie S.

Rachel M.

"The desire to drink alcohol disappeared after just my first two treatments. By my third and fourth, I noticed a real shift, I could pause instead of reacting, and my self-awareness and ability to recognize my own emotions grew so much. I'd recommend this to anyone who feels out of touch with themselves or overwhelmed by anxiety. The possibility of living without that constant weight is immense."

Rachel M.

Ready to get support?

  • No commitment
  • Real humans
  • Free verification
  • HIPAA-compliant

How to get started

We've made this as simple as we can.

01

Check

Take the 30-second quiz and share your insurance details so we can check coverage for free.

02

Consult

Meet with a Psycle Health Care Coordinator to confirm if a partner clinic is a fit.

03

Evaluate

Speak with a licensed medical professional to confirm you're a candidate.

04

Authorize

The clinic will submit a prior authorization to your insurance, which takes 5-7 days on average.

05

Improve

Begin twice-weekly starting sessions, with our team supporting you through every visit.

Frequently asked questions about the evaluation.

A licensed psychiatrist at the partner clinic nearest you reviews your medication history, your current symptoms, and any safety factors. Together you'll discuss whether SPV, TMS, or another path is the best fit. Psycle Health verifies your insurance for free in parallel.

No. The evaluation is the perfect time to consider this choice further. Your psychiatrist recommends a path based on your history, your goals, and your safety profile. Many patients qualify for more than one option; some only fit one. Considering your options together is what the clinical conversation is for.

About 45 - 60 minutes for the clinical visit, plus a brief intake call beforehand to verify insurance and gather records. Most patients leave the evaluation with a clear next step towards SPV or TMS, and a starting date if they want to proceed.

Yes. The partner clinic doesn't charge for the initial consultation. Insurance verification through Psycle Health is also free. There's no obligation to start SPV or TMS treatment.

SPV (esketamine) is an FDA-approved nasal spray for adults whose depression hasn't responded to at least two oral antidepressants. It works on the glutamate system, can produce measurable effects within 24 hours, and is taken in-clinic with two hours of monitoring afterward. You'll be asked to arrange a ride home, and be able to drive again the next day.

TMS (transcranial magnetic stimulation) is an FDA-cleared treatment that uses gentle magnetic pulses to reactivate the part of the brain that depression can subdue. Sessions are about 20 minutes, drug-free, with no sedation, and you can return to normal activities right away afterwards. A standard course runs five days a week for six weeks.

Most major commercial plans and Medicare cover both, with prior authorization. Psycle Health and the partner clinic handle the paperwork for whichever path you and your psychiatrist choose, at no cost.

We'll tell you honestly and walk you through alternative approaches. If a different path is right for you, we'll point you to it. If it's possible these approaches might be right for you in the future, e.g., after tapering off a current medication, we'll arrange a future free consultation.

Fill out the form. A Psycle Health care coordinator calls within 24 hours to verify your insurance and book the evaluation with the clinic nearest you. From form to evaluation is usually under a week, with treatment for the earliest possible appointment following a successful evaluation.

The male presentation of depression, irritability, flatness, fatigue, overwork, overlaps heavily with what gets called burnout. A psychiatrist can tell the difference in one proper evaluation.

Psycle matches people to treatment and doesn't touch claims, ratings, or benefits determinations. For how private treatment interacts with your specific rating, talk to your VSO.

No. These treatments target depression, which in men often gets mistaken for low T because the symptoms overlap. A psychiatrist can help untangle which problem is driving what.

You haven't run out of options. You may just not have been offered the right ones yet.

Schedule a free call. We'll verify your insurance and talk through your history. And together with a psychiatrist, we'll help you map a real next step.